Research & Guides · Strength

Strength, written by clinicians.

7 physician-reviewed articles on strength — what each compound does at the cellular level, who it's for, and what the evidence does and doesn't establish.

Articles

Pages

Avg Read

10 Min

Updated

2026

Comparing sermorelin and tesamorelin, two GHRH analogs

Featured · Strength

Sermorelin vs. Tesamorelin: How the Two GHRH Analogs Actually Differ

Sermorelin vs. tesamorelin: both are GHRH analogs, but tesamorelin is FDA-approved for one narrow condition while sermorelin is compounded for growth-hormone-axis support. An honest, physician-reviewed comparison.

Dr. Richard Dentico, MD · 7 min read

Read article

A gloved clinician's hand holding a prepared syringe in a clean clinical setting, representing physician-prescribed sermorelin dosing.

Strength · 8 min read

Sermorelin Dosage: What Actually Determines Your Protocol

Sermorelin dosage has no universal number. Clinic protocols commonly describe starting around 200–300 mcg by subcutaneous injection before bed, a figure from practice rather than a trial — a physician sets yours by age, weight, goals, and response. Here's what drives it.

Strength · 10 min read

Sermorelin Side Effects: What to Actually Expect

Sermorelin side effects, explained honestly by a physician — the common mild ones, the rare serious ones, how long they last, and when to call your doctor.

Man sleeping peacefully in morning sunlight — sermorelin acts on the pituitary's own pulsatile growth hormone release, unlike exogenous HGH.

Strength · 12 min read

Sermorelin vs HGH: The Real Difference, Explained

Sermorelin and HGH both raise growth hormone — but in opposite ways. One signals your own pituitary to release GH in its natural pulsatile rhythm; the other floods the hormone in directly and bypasses your feedback loop. Here's the difference that actually matters.