Longevity Articles | Protocol MD

The real reasons behind waking up at 3am every night

Featured · Longevity

Why Do I Wake Up at 3AM? The Real Reasons (and How to Fix It)

Waking up at 3am almost every night usually isn't random — it's most often your cortisol rhythm, a blood-sugar dip, alcohol, or stress. A physician-reviewed look at the real causes and what actually helps.

Dr. Richard Dentico, MD · 7 min read

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The common causes behind always feeling tired

Longevity · 7 min read

Why Am I Always Tired? The Real Causes (and When to See a Doctor)

The most common reasons you're always tired are poor sleep, blood-sugar swings, chronic stress, dehydration, and under-recovery — but persistent, unexplained fatigue can signal a medical issue. An honest, physician-reviewed guide to the causes.

The everyday factors behind getting sick so often

Longevity · 7 min read

Why Am I Getting Sick So Often? Causes and When to See a Doctor

Getting sick constantly usually comes down to sleep debt, chronic stress, nutrition gaps, and exposure — not a broken immune system. Here's what actually drives frequent illness, and when it's worth seeing a doctor.

Persistent exhaustion and stress, the symptoms behind the adrenal fatigue label

Longevity · 10 min read

What Is Adrenal Fatigue? The Honest Answer — and What's Actually Causing Your Symptoms

Adrenal fatigue isn't a recognized medical diagnosis — but the symptoms are real. A physician-reviewed look at what the evidence says, what's actually causing exhaustion and brain fog, and what genuinely helps.

NMN as a precursor to NAD+ for cellular health

Longevity · 9 min read

NMN Benefits: What the Science Actually Shows (and Why the Form Matters)

NMN is an oral precursor your body converts into NAD+. Early research suggests it can raise NAD+ levels, but human evidence is still developing — and how well it works depends on absorption. An honest, physician-reviewed look.

Managing chronic stress to support healthy cortisol levels

Longevity · 9 min read

High Cortisol: Signs, Causes, and How to Lower It Naturally

High cortisol often shows up as poor sleep, low or "wired but tired" energy, anxiety, and appetite changes — usually from chronic stress. A physician's guide to the signs, causes, and how to lower cortisol naturally.

A woman lifting a barbell in a gym, representing steady, natural energy and strength

Longevity · 8 min read

How to Increase Energy Naturally (and Why It Declines With Age)

The best natural ways to increase energy are consistent sleep, movement, steady blood sugar, stress management, and hydration — and they matter more with age as cellular energy production slows. A physician's guide.

Longevity, written by clinicians.