Research & Guides · Longevity

Longevity, written by clinicians.

25 physician-reviewed articles on longevity — what each compound does at the cellular level, who it's for, and what the evidence does and doesn't establish.

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9 Min

Updated

2026

Featured · Longevity

What Is NAD+? The Coenzyme, Why It Declines and What the Evidence Shows

What NAD+ is, why your levels fall with age, and how oral precursors, injections and IV compare. The mechanism, and the honest state of the evidence.

Richard Dentico, MD · 16 min read

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Glutathione vial and syringe prepared for a physician-prescribed injection

Longevity · 9 min read

Glutathione Dosage: What the Research Used, by Route

The doses used in published research, broken out by route — and why the injectable number is a prescribing decision rather than a label instruction.

Open notebook and laptop in morning light, illustrating an article on how to read NAD+ reviews critically

Longevity · 11 min read

NAD+ Reviews: What They Measure and What They Miss

NAD+ reviews contradict each other partly because they are not reviewing the same thing. Most describe an oral capsule; most readers are weighing an injection.

Compounded sermorelin vial on a clinical surface, illustrating an article reviewing patient-reported sermorelin results

Longevity · 12 min read

Sermorelin Reviews: What Patients Report and What Holds Up

Sermorelin reviews contradict each other because they come from three different populations asking three different questions. Here is how to tell which one you are reading.