Research & Guides · Weight Loss

Weight Loss, written by clinicians.

22 physician-reviewed articles on weight loss — what each compound does at the cellular level, who it's for, and what the evidence does and doesn't establish.

Articles

Pages

Avg Read

9 Min

Updated

2026

A woman sitting by a tall window in a quiet room, looking out at overcast daylight

Featured · Weight Loss

Tirzepatide Long-Term Side Effects: What We Know and What We Don't

Tirzepatide long-term side effects: its longest randomized trial ran about three years, so genuinely long-term data doesn't exist yet. Here's exactly what that window shows, what it can't, and what to monitor.

Dr. Richard Dentico, MD · 9 min read

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Facial volume, protein and strength training as the levers that matter

Weight Loss · 9 min read

Ozempic Face: What Causes It and How to Avoid It

"Ozempic face" is facial volume loss from rapid weight loss, not a direct drug effect. Here's the mechanism, why it travels with hair shedding and muscle loss, and how to limit it.

A protein shake and eggs, both high in sulfur-containing amino acids

Weight Loss · 10 min read

Sulfur Burps on GLP-1 Medications: Causes and How to Get Rid of Them

Sulfur burps on Ozempic, Wegovy, Zepbound, Mounjaro, or compounded GLP-1s come from food sitting longer and fermenting. Here's what causes them and what actually helps.

Diagram showing the three subcutaneous injection sites: abdomen, thigh, and upper arm

Weight Loss · 12 min read

Where to Inject Semaglutide: Sites, Rotation, and What Actually Matters

Where to inject semaglutide: under the skin of the abdomen, thigh, or upper arm. Site choice doesn't change how well it works — rotating between sites is the part that does.

A hand cradling a bowl of ginger and lemon tea

Weight Loss · 9 min read

Semaglutide Nausea: Why It Happens and How to Relieve It

Nausea is the most common semaglutide side effect. Here's the mechanism, the timing pattern most people miss, what actually helps, and the symptoms that mean you should be seen.

Hydration and electrolyte support while taking semaglutide

Weight Loss · 7 min read

Semaglutide and Diarrhea: Why It Happens and When to Be Concerned

Diarrhea is a common semaglutide side effect — and the same medication can also cause constipation. Here's why both happen, what helps, and the dehydration signs that mean you should be seen.

Fiber and hydration support while taking semaglutide

Weight Loss · 7 min read

Semaglutide and Constipation: Why It Happens and What Helps

Constipation is one of the most common side effects of semaglutide. Here's the mechanism behind it, what actually helps, and the symptoms that mean you should be seen rather than wait it out.