Protocol MD

Research & Guides

The peptide library, written by clinicians.

62 long-form articles on peptide therapy — what each compound does at the cellular level, who it's for, what the FDA says about it, and where the gray-market vendors get the story wrong. Every guide is reviewed by a US-licensed physician and updated as evidence evolves.

Articles

62

Categories

4

Avg Read

10 Min

Updated

2026

Man resting in bed in soft morning light

Featured · Longevity

Sermorelin Before and After: The Realistic Timeline, Month by Month

Every sermorelin before-and-after page on the internet has a timeline table and a stock photo of someone at the gym. Here is the version a physician would sign: what changes, in what order, over how long — and the limitations named before the claims.

Dr. Richard Dentico, MD · 11 min read

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Comparing Zepbound and Wegovy

Weight Loss · 12 min read

Zepbound vs Wegovy: How the Two Weight-Loss Drugs Compare

Zepbound vs Wegovy: Zepbound is tirzepatide, Wegovy is semaglutide. They are approved for different conditions, priced very differently, and one leads on average weight loss.

A guide to tirzepatide side effects

Weight Loss · 11 min read

Tirzepatide Side Effects: What to Expect and What to Watch For

Most tirzepatide side effects are gastrointestinal and settle with time. Here's the full picture — common effects, the serious ones, the eye signal, and what compounded formulations add.

A woman sitting by a tall window in a quiet room, looking out at overcast daylight

Weight Loss · 9 min read

Tirzepatide Long-Term Side Effects: What We Know and What We Don't

Tirzepatide long-term side effects: its longest randomized trial ran about three years, so genuinely long-term data doesn't exist yet. Here's exactly what that window shows, what it can't, and what to monitor.

Facial volume, protein and strength training as the levers that matter

Weight Loss · 9 min read

Ozempic Face: What Causes It and How to Avoid It

"Ozempic face" is facial volume loss from rapid weight loss, not a direct drug effect. Here's the mechanism, why it travels with hair shedding and muscle loss, and how to limit it.

A protein shake and eggs, both high in sulfur-containing amino acids

Weight Loss · 10 min read

Sulfur Burps on GLP-1 Medications: Causes and How to Get Rid of Them

Sulfur burps on Ozempic, Wegovy, Zepbound, Mounjaro, or compounded GLP-1s come from food sitting longer and fermenting. Here's what causes them and what actually helps.

Diagram showing the three subcutaneous injection sites: abdomen, thigh, and upper arm

Weight Loss · 12 min read

Where to Inject Semaglutide: Sites, Rotation, and What Actually Matters

Where to inject semaglutide: under the skin of the abdomen, thigh, or upper arm. Site choice doesn't change how well it works — rotating between sites is the part that does.

  • 503A US Pharmacy
  • Physician-Prescribed
  • USP-Compliant Compounding

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