Protocol MD

Research & Guides

The peptide library, written by clinicians.

48 long-form articles on peptide therapy — what each compound does at the cellular level, who it's for, what the FDA says about it, and where the gray-market vendors get the story wrong. Every guide is reviewed by a US-licensed physician and updated as evidence evolves.

Articles

48

Categories

4

Avg Read

9 Min

Updated

2026

Persistent exhaustion and stress, the symptoms behind the adrenal fatigue label

Featured · Longevity

What Is Adrenal Fatigue? The Honest Answer — and What's Actually Causing Your Symptoms

Adrenal fatigue isn't a recognized medical diagnosis — but the symptoms are real. A physician-reviewed look at what the evidence says, what's actually causing exhaustion and brain fog, and what genuinely helps.

Dr. Richard Dentico, MD · 10 min read

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NMN as a precursor to NAD+ for cellular health

Longevity · 9 min read

NMN Benefits: What the Science Actually Shows (and Why the Form Matters)

NMN is an oral precursor your body converts into NAD+. Early research suggests it can raise NAD+ levels, but human evidence is still developing — and how well it works depends on absorption. An honest, physician-reviewed look.

Managing chronic stress to support healthy cortisol levels

Longevity · 9 min read

High Cortisol: Signs, Causes, and How to Lower It Naturally

High cortisol often shows up as poor sleep, low or "wired but tired" energy, anxiety, and appetite changes — usually from chronic stress. A physician's guide to the signs, causes, and how to lower cortisol naturally.

A woman lifting a barbell in a gym, representing steady, natural energy and strength

Longevity · 8 min read

How to Increase Energy Naturally (and Why It Declines With Age)

The best natural ways to increase energy are consistent sleep, movement, steady blood sugar, stress management, and hydration — and they matter more with age as cellular energy production slows. A physician's guide.

A gloved clinician's hand holding a prepared syringe in a clean clinical setting, representing physician-prescribed sermorelin dosing.

Strength · 8 min read

Sermorelin Dosage: What Actually Determines Your Protocol

Sermorelin is typically started around 200–300 mcg by subcutaneous injection before bed, but there's no universal dose — a physician sets yours by age, weight, goals, and response. Here's what drives it.

Physician reviewing an individualized NAD+ dosing plan with a patient

Longevity · 7 min read

NAD+ Dosage: What Actually Determines Your Injection Protocol

NAD+ injection dosing is individualized — there's no universal chart. Here's the general ranges people use, how frequency works, and what a physician weighs to set your dose.

Close-up of a woman's sunlit face, neck, and shoulders with dewy, healthy-looking skin against a clear blue sky.

Longevity · 9 min read

NAD+ IV Therapy: Benefits, Cost, and How Injection Compares

NAD IV therapy, explained by a physician: what it is, the benefits people pursue, cost, and how clinic IV drips compare to a convenient at-home NAD+ injection.

503A US PharmacyPhysician-PrescribedUSP-Compliant Compounding

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