Protocol MD

Research & Guides

The peptide library, written by clinicians.

62 long-form articles on peptide therapy — what each compound does at the cellular level, who it's for, what the FDA says about it, and where the gray-market vendors get the story wrong. Every guide is reviewed by a US-licensed physician and updated as evidence evolves.

Articles

62

Categories

4

Avg Read

10 Min

Updated

2026

Comparing sermorelin and tesamorelin, two GHRH analogs

Featured · Strength

Sermorelin vs. Tesamorelin: How the Two GHRH Analogs Actually Differ

Sermorelin vs. tesamorelin: both are GHRH analogs, but tesamorelin is FDA-approved for one narrow condition while sermorelin is compounded for growth-hormone-axis support. An honest, physician-reviewed comparison.

Dr. Richard Dentico, MD · 7 min read

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Persistent exhaustion and stress, the symptoms behind the adrenal fatigue label

Longevity · 10 min read

What Is Adrenal Fatigue? The Honest Answer — and What's Actually Causing Your Symptoms

Adrenal fatigue isn't a recognized medical diagnosis — but the symptoms are real. A physician-reviewed look at what the evidence says, what's actually causing exhaustion and brain fog, and what genuinely helps.

NMN as a precursor to NAD+ for cellular health

Longevity · 9 min read

NMN Benefits: What the Science Actually Shows (and Why the Form Matters)

NMN benefits start with one fact: NMN is an oral precursor your body converts into NAD+. Early research suggests it can raise NAD+ levels, but human evidence is still developing — and how well it works depends on absorption. An honest, physician-reviewed look.

Managing chronic stress to support healthy cortisol levels

Longevity · 9 min read

High Cortisol: Signs, Causes, and How to Lower It Naturally

High cortisol from chronic stress is often linked to poor sleep, "wired but tired" energy, anxiety and appetite changes, but only testing confirms it. A physician's guide to the signs, causes, testing and how to lower cortisol naturally.

A woman lifting a barbell in a gym, representing steady, natural energy and strength

Longevity · 8 min read

How to Increase Energy Levels Naturally (and Why They Decline With Age)

How to increase energy levels naturally: the best-supported ways are consistent sleep, movement, balanced meals, stress management and hydration, and they matter more with age. A physician's guide.

A gloved clinician's hand holding a prepared syringe in a clean clinical setting, representing physician-prescribed sermorelin dosing.

Strength · 8 min read

Sermorelin Dosage: What Actually Determines Your Protocol

Sermorelin dosage has no universal number. Clinic protocols commonly describe starting around 200–300 mcg by subcutaneous injection before bed, a figure from practice rather than a trial — a physician sets yours by age, weight, goals, and response. Here's what drives it.

Physician reviewing an individualized NAD+ dosing plan with a patient

Longevity · 7 min read

NAD+ Dosage: What Actually Determines Your Injection Protocol

NAD+ dosage for injections is individualized — there's no universal chart. Here's the general ranges people use, how frequency works, and what a physician weighs to set your dose.

  • 503A US Pharmacy
  • Physician-Prescribed
  • USP-Compliant Compounding

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